Restrictive versus Liberal Rate of Extracorporeal Volume Removal Evaluation in Acute Kidney Injury (RELIEVE-AKI): a pilot clinical trial protocolRaghavan Murugan, Chung-Chou H Chang, Maham Raza, Nasrin Nikravangolsefid, David T Huang, Paul M Palevsky, Kianoush Kashani, , for the (RELIEVE-AKI) Study Investigators, Ali Al-Khafaji, Brad Butcher, Philip Lamberty, Firas Abdulmajeed, Scott Gunn, Andrea KattahSee the full list of authors
7 July 2023
Longitudinal trajectories of sedation level and clinical outcomes in patients who are mechanically ventilated based on a group-based trajectory model: a prospective, multicentre, longitudinal and observational study in KoreaDong-gon Hyun, Jee Hwan Ahn, Ha-Yeong Gil, Chung Mo Nam, Choa Yun, Chae-Man Lim
27 June 2023
Critical Care Cycling to Improve Lower Extremity Strength (CYCLE): protocol for an international, multicentre randomised clinical trial of early in-bed cycling for mechanically ventilated patientsMichelle E Kho, Julie Reid, Alexander J Molloy, Margaret S Herridge, Andrew J Seely, Jill C Rudkowski, Lisa Buckingham, Diane Heels-Ansdell, Tim Karachi, Alison Fox-Robichaud, Ian M Ball, Karen E A Burns, Joseph R Pellizzari, Christopher Farley, Sue BerneySee the full list of authors
23 June 2023
Protocol for a systematic review and meta-analysis assessing conservative versus liberal intravenous fluid administration in patients with sepsis or septic shock at risk of fluid overloadAadil Bharwani, María Lucía Pérez, Marina Englesakis, Tine Sylvest Meyhoff, Anders Perner, Praleene Sivapalan, Mary Elizabeth Wilcox
24 May 2023
Critical illness myopathy and trajectory of recovery in acute kidney injury requiring continuous renal replacement therapy: a prospective observational trial protocolJ Pedro Teixeira, Benjamin R Griffin, Chaitanya Anil Pal, Felipe González-Seguel, Nathanial Jenkins, Beth M Jones, Yuri Yoshida, Naomi George, Hayley Puffer Israel, Lama Ghazi, Javier A Neyra, Kirby P Mayer
22 May 2023
What counts as patient-important upper gastrointestinal bleeding in the ICU? A mixed-methods study protocol of patient and family perspectivesDeborah J Cook, Marilyn E Swinton, Karla D Krewulak, Kirsten Fiest, Joanna C Dionne, Sylvie Debigare, Gordon H Guyatt, Shipra Taneja, Waleed Alhazzani, Karen E A Burns, John C Marshall, John G Muscedere, Audrey Gouskos, Simon Finfer, Adam M DeaneSee the full list of authors
19 May 2023
Bubble-PAPR: a phase 1 clinical evaluation of the comfort and perception of a prototype powered air-purifying respirator for use by healthcare workers in an acute hospital settingBrendan A McGrath, Clifford L Shelton, Angela Gardner, Ruth Coleman, James Lynch, Peter G Alexander, Glen Cooper
8 May 2023
Relationship between grip strength during hospitalisation and mental disorders after discharge in critically ill patients: a post-hoc analysis of a prospective observational studyAyano Notsuyu, Hiromu Naraba, Keibun Liu, Daisuke Ikechi, Hidehiko Nakano, Masaki Mochizuki, Yuji Takahashi, Shinichi Watanabe, Yasunari Morita, Toru Kotani, Kensuke Nakamura
5 May 2023
Development of Core Outcome Sets for trials on the management of Atrial fiBrillAtion in Critically Unwell patientS (COS-ABACUS): a protocolBrian Johnston, Ruaraidh A Hill, Bronagh Blackwood, Gregory Y H Lip, Ingeborg D Welters
29 April 2023
Neurologic Physiology after Removal of Therapy (NeuPaRT) study: study protocol of a multicentre, prospective, observational, pilot feasibility study of neurophysiology after withdrawal of life-sustaining measuresTeneille Gofton, Sonny Dhanani, Maureen Meade, John Gordon Boyd, Erika Chamberlain, Jennifer Chandler, Michaël Chassé, Nathan B Scales, Yun-Hee Choi, Frédérick D'Aragon, Derek Debicki, Shane English, Tadeu A Fantaneanu, Andreas H Kramer, Julie KrommSee the full list of authors
27 April 2023