Intensive care

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ExtraCorporeal Membrane Oxygenation in the therapy for REfractory Septic shock with Cardiac function Under Estimated (ECMO-RESCUE): study protocol for a prospective, multicentre, non-randomised cohort study

Wei-yan Chen, Ze-bin Guo, Tian-yu Kong, Wei-xiao Chen, Xiao-hua Chen, Qilin Yang, Yi-chao Wen, Qi-rui Wen, Feng Zhou, Xu-ming Xiong, De-liang Wen, Zhen-hui Zhang

10 June 2024

Comparison of outcomes from tunnelled femorally inserted central catheters and peripherally inserted central catheters: a propensity score-matched cohort study

Craig McManus, Nicholas Mifflin, Renz Rivera, Sophie Vause, Ton Tran, Matthew Ostroff, Lorenza Harrowell, Steven Frost, Evan Alexandrou

17 May 2024

Association between septic shock and tracheal injury score in intensive care unit patients with invasive ventilation: a prospective single-centre cohort study in China

Pei Zhang, Qilin Yang, Chunhua Yin, Zhigang Cai, Huaihai Lu, Haitao Li, Liwen Li, Ye Tian, Long Bai, Lining Huang

13 May 2024

Sex and gender-based analysis and diversity metric reporting in acute care trials published in high-impact journals: a systematic review

David Granton, Myanca Rodrigues, Valeria Raparelli, Kimia Honarmand, Arnav Agarwal, Jan O Friedrich, Benedetta Perna, Riccardo Spaggiari, Valeria Fortunato, Gianluca Risdonne, Michelle Kho, Sandra VanderKaay, Dipayan Chaudhuri, Carolina Gomez-Builes, Frédérick D'AragonSee the full list of authors

7 May 2024

Air leak test in the Paediatric Intensive Care Unit (ALTIPICU): rationale and protocol for a prospective multicentre observational study

Boris Lacarra, Aurélie Hayotte, Jérôme Naudin, Arielle Maroni, Guillaume Geslain, Géraldine Poncelet, Michael Levy, Matthieu Resche-Rigon, Stéphane Dauger

30 April 2024

Metformin for sepsis-associated AKI: a protocol for the Randomized Clinical Trial of the Safety and FeasibiLity of Metformin as a Treatment for sepsis-associated AKI (LiMiT AKI)

Ivan E Saraiva, Natsumi Hamahata, David T Huang, Sandra L Kane-Gill, Ryan M Rivosecchi, Sruti Shiva, Thomas D Nolin, Xinlei Chen, John Minturn, Chung-Chou H Chang, Xiaotong Li, John Kellum, Hernando Gómez

30 April 2024

Healthcare and economic cost burden of emergency medical services treated non-traumatic shock using a population-based cohort in Victoria, Australia

Jason E Bloom, Emily Nehme, Elizabeth Davida Paratz, Luke Dawson, Adam J Nelson, Jocasta Ball, Amminadab Eliakundu, Aleksandr Voskoboinik, David Anderson, Stephen Bernard, Aidan Burrell, Andrew A Udy, David Pilcher, Shelley Cox, William ChanSee the full list of authors

28 April 2024

Effect of acyclovir therapy on the outcome of mechanically ventilated patients with lower respiratory tract infection and detection of herpes simplex virus in bronchoalveolar lavage: protocol for a multicentre, randomised controlled trial (HerpMV)

Stefan Hagel, Nicole Brillinger, Sebastian Decker, Maria Deja, Christian Ertmer, Sandra Fiedler, Philipp Franken, Markus Heim, Markus A Weigand, Alexander Zarbock, Mathias W Pletz, , SepNet Critical Care Trials Group, Johannes Ehler, Frank BloosSee the full list of authors

25 April 2024

Safety of different concentrations of glycerine enema for meconium evacuation in preterm infants: study protocol for a randomised controlled trial

Xia Li, Changhong Liu, Jing Zhang, Qingling Yu, Xuemei Guo, Yanling Hu, Jing Shi

23 April 2024

Epirubicin for the Treatment of Sepsis and Septic Shock (EPOS-1): study protocol for a randomised, placebo-controlled phase IIa dose-escalation trial

Daniel Thomas-Rüddel, Michael Bauer, Luís Ferreira Moita, Christiane Helbig, Peter Schlattmann, Johannes Ehler, Tim Rahmel, Patrick Meybohm, Matthias Gründling, Heiko Schenk, Thomas Köcher, Frank M Brunkhorst, Markus Gräler, Ann-Julika Heger, Sebastian WeisSee the full list of authors

22 April 2024

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