Impact of increasing post-filter ionised calcium target on regional citrate anticoagulation efficacy in ICU continuous renal replacement therapy: the non-inferiority randomised controlled Ca-CIBLE protocolMona Assefi, Rayan Braik, Arthur James, Noémie Clavieras, Elodie Baron, Florian Blanchard, Jean-Michel Constantin
26 September 2024
Efficacy and safety of esketamine hydrochloride adjunct to sufentanil in non-surgical patients under mechanical ventilation in the ICU (SENSATION trial): protocol for a multicentre, single-blind, randomised controlled trialYi Long, Donghuang Hong, Haibin Ni, Dandan Zhou, Tingfa Zhou, Songwu Liu, Xiang Luo, Qian Liu, Rui Li, Zhengying Jiang, Lu Ke
25 September 2024
Early intravenous high-dose vitamin C in postcardiac arrest shock (VICEPAC): study protocol for a randomised, single-blind, open-label, multicentre, controlled trialJonathan Chelly, Noemie Peres, Ghada Sboui, Julien Maizel, Marion Beuzelin, Olivier Nigeon, Sebastien Preau, Ly Van Phach Vong, Fabienne Tamion, Fabien Lambiotte, Nicolas Deye, Thibaut Bertrand, Hélène Behal, Laurent Ducros, Christophe Vinsonneau
24 September 2024
Comparison of side-hole and step-tip catheters for patients requiring continuous renal replacement therapy in intensive care units: study protocol for a randomised controlled trialZhifeng Zhou, Chen Liu, Yingying Yang, Fang Wang, Sheng Zhang, Ling Zhang, Ping Fu
20 September 2024
SIGNET: protocol for a multicentre, single-blind prospective, group sequential, randomised controlled trial to evaluate the benefits of a single dose of simvastatin given to potential organ donors declared dead by neurological criteria on outcomes in organ recipientsAmy Evans, Phil Mawson, Helen Thomas, Katie Keen, Christopher JE Watson, Daniel Francis McAuley, Guy A MacGowan, Neil S Sheerin, Andrew Fisher, James Shaw, Hilary Yates, Andrea Fallow, Daphne Kounali, Jennifer Banks, Margaret StevensSee the full list of authors
18 September 2024
Multinational trends in sepsis mortality between 1985 and 2019: a temporal analysis of the WHO Mortality DatabaseMatthieu Komorowski, Justin D Salciccioli, Joseph Shalhoub, Anthony C Gordon, Dominic C Marshall
12 September 2024
Hyperangulated versus Macintosh blades for intubation with videolaryngoscopy in ICU: the randomised multicentre INVIBLADE-ICU trial study protocolManuel Taboada, Ana Estany-Gestal, Jorge Fernández, Olalla Vazquez, Azucena Pajares, Fernando Ramasco, Sara Martínez, Irene Vallejo, Ana Pérez, Pablo Rama-Maceiras, María Bermúdez, Mercedes Power, Raquel García-Álvarez, Inmaculada Fernández-Villa, Jose Luis AguileraSee the full list of authors
5 September 2024
Efficacy and safety of dynamic arterial elastance for weaning vasopressor support in septic shock patients: a randomised controlled trial protocolJorge Iván Alvarado Sánchez, Andrea Valentina Montañez-Nariño, Yenny Rocio Cárdenas-Bolivar, Maria Valentina Stozitzky-Ríos, Andrés Felipe Mora-Salamanca
7 August 2024
Use of pressure muscle index to guide pressure support ventilation setting: a study protocol and statistical plan for a prospective randomised controlled proof-of-concept trialRan Gao, Yan-Lin Yang, Linlin Zhang, Ming-Yue Miao, Jian-Xin Zhou
3 August 2024
Associations of the staffing structure of intensive care units and high care units on in-hospital mortality among patients with sepsis: a cross-sectional study of Japanese nationwide claims dataTakeshi Umegaki, Kota Nishimoto, Takahiko Kamibayashi
30 July 2024