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Haematology (incl blood transfusion)

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Protocol for a multicentric, double-blind, randomised controlled trial of hyperbaric oxygen therapy (HBOT) versus sham for treating vaso-occlusive crisis (VOC) in sickle cell disease (SCD) in patients aged 8 years or older (HBOT-SCD study)
Jerome Stirnemann, Jacques Serratrice, Tamara Mann, Pierre Louge, Combescure Christophe, Kaveh Samii, Rodrigue Pignel, Thomas Agoritsas, Marc Ansari, Giovanna Cannas, Yves Chalandon, Laurent Cimasoni, Pierre Cougoul, Benoit Desgraz, Alain GervaixSee the full list of authors

28 November 2024

Identifying thresholds for meaningful improvements in NTDT-PRO scores to support conclusions about treatment benefit in clinical studies of patients with non-transfusion-dependent beta-thalassaemia: analysis of pooled data from a phase 2, double-blind, placebo-controlled, randomised trial
Ali T Taher, Khaled M Musallam, Vip Viprakasit, Antonis Kattamis, Jennifer Lord-Bessen, Aylin Yucel, Shien Guo, Christopher G Pelligra, Alan L Shields, Jeevan K Shetty, Mrudula B Glassberg, Luciana Moro Bueno, Maria Domenica Cappellini

14 November 2024

Acceptability, barriers and facilitators of using dried blood spots-point-of-care testing for sickle cell disease in Africa: an implementation science protocol for a multinational qualitative study
Obiageli Eunice Nnodu, Nchangwi Syntia Munung, Lulu Chirande, Catherine Chunda-Liyoka, Sarah Kiguli, Fred Stephen Sarfo, Boubacari Ali Touré, Emmanuel Balandya, Aldiouma Guindo, Patience Kuona, Kevin Esoh, Mario Jonas, Maxwell Nwegbu, Upendo Masamu, Jack MorriceSee the full list of authors

7 November 2024