Surgery

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Pathway Of Low Anterior Resection syndrome (LARS) relief after Surgery (POLARiS): protocol for an international, open-label, multi-arm, phase 3 randomised superiority trial within a cohort, with economic evaluation, process evaluation and qualitative sub-study, to explore the natural history of LARS and compare transanal irrigation and sacral neuromodulation to optimised conservative management for people with major LARS following a high or low anterior resection for colorectal cancer
Julie Croft, Emily Farrow, Alexandra Harriet Coxon-Meggy, Katie Gordon, Neil Corrigan, Hannah Mather, Deborah D Stocken, Megan Dale, Huey Yi Chong, Judith White, Laura Knight, Alun Meggy, Christina Lloydwin, Betty Tan, Ashley DouglasSee the full list of authors

3 February 2025