Evaluation of the effectiveness and safety of oral vancomycin versus placebo in the prevention of recurrence of Clostridioides difficile infection in patients under systemic antibiotic therapy: a phase III, randomised, double-blind clinical trialRafael San-Juan, Julia Origuen, Karen Campion, Mario Fernández-Ruiz, Beatriz Diaz-Pollan, Alejandro Callejas-Diaz, Giancarlo Candela, Maria Angeles Orellana, David Lora, Irene Llorente Muñoz, Maria Teresa Garcia, Maite Martinez-Uña, Jose Miguel Ferrari, Jose M Aguado
13 September 2023
Randomised, open-label, non-inferiority clinical trial on the efficacy and safety of a 7-day vs 14-day course of antibiotic treatment for uncomplicated enterococcal bacteraemia: the INTENSE trial protocolNatalia Maldonado, Clara M Rosso-Fernández, Inés Portillo-Calderón, Irene Borreguero Borreguero, Enriqueta Tristán-Clavijo, Zaira R Palacios-Baena, Elena Salamanca, Felipe Fernández-Cuenca, Marina De-Cueto, Emilio Stolz-Larrieu, Jesús Rodriguez-Baño, Luis Eduardo López-Cortés
6 September 2023
Impact of 1-hour and 3-hour sepsis time bundles on antibiotic use in emergency departments in Queensland, Australia: a before-and-after cohort studyKathryn Wilks, Donna Mason, Michael Rice, Robert Seaton, Lyndell Redpath, Kristen Gibbons, Endrias Ergetu, Paul Lane, Balasubramanian Venkatesh
5 September 2023
Penicillin allergy status and its effect on antibiotic prescribing, patient outcomes and antimicrobial resistance (ALABAMA): protocol for a multicentre, parallel-arm, open-label, randomised pragmatic trialKelsey Fiona Armitage, Catherine E Porter, Shadia Ahmed, Johanna Cook, Jenny Boards, Emily Bongard, Christopher C Butler, Kate Corfield, Mina Davoudianfar, Ushma Galal, Philip Howard, Ruben Mujica-Mota, Razan Saman, Marta Santillo, Sinisa SavicSee the full list of authors
4 September 2023
Burden of lower respiratory infections and associated risk factors across regions in Ethiopia: a subnational analysis of the Global Burden of Diseases 2019 studyAmanuel Yigezu, Awoke Misganaw, Fentabil Getnet, Tezera Moshago Berheto, Ally Walker, Ababi Zergaw, Firehiwot Abebe Gobena, Muluken Argaw Haile, Alemayehu Hailu, Solomon Tessema Memirie, Dereje Mengistu Tolosa, Semagn Mekonnen Abate, Mesafint Molla Adane, Gizachew Taddesse Akalu, Addis AkliluSee the full list of authors
4 September 2023
Changes in weight, body composition and metabolic parameters after switch to dolutegravir/lamivudine compared with continued treatment with dolutegravir/abacavir/lamivudine for virologically suppressed HIV infection (The AVERTAS trial): a randomised, open-label, superiority trial in Copenhagen, DenmarkKaren Brorup Heje Pedersen, Andreas Knudsen, Søren Møller, Hartwig Roman Siebner, Jens Dahlgaard Hove, Jan Gerstoft, Thomas Benfield
21 August 2023
Burden and seasonal distribution of malaria in Ziquala district, Northeast Ethiopia: a 5-year multi-centre retrospective studyHabtu Debash, Habtye Bisetegn, Hussen Ebrahim, Mihret Tilahun, Zelalem Dejazmach, Nigatu Getu, Daniel Getacher Feleke
18 August 2023
Does monoclonal antibody treatment for COVID-19 impact short and long-term outcomes in a large generalisable population? A retrospective cohort study in the USADaniel Griffin, Chace McNeil, James Okusa, Diana Berrent, Yinglong Guo, Sarah E Daugherty
8 August 2023
Platform adaptive trial of novel antivirals for early treatment of COVID-19 In the community (PANORAMIC): protocol for a randomised, controlled, open-label, adaptive platform trial of community novel antiviral treatment of COVID-19 in people at increased risk of more severe diseaseOghenekome Gbinigie, Emma Ogburn, Julie Allen, Jienchi Dorward, Melissa Dobson, Tracie-Ann Madden, Ly-Mee Yu, David M Lowe, Najib Rahman, Stavros Petrou, Duncan Richards, Kerenza Hood, Mahendra Patel, Benjamin R Saville, Joe MarionSee the full list of authors
7 August 2023
Efficacy of single-dose oral secnidazole for the treatment of trichomoniasis in women co-infected with trichomoniasis and bacterial vaginosis: a post hoc subgroup analysis of phase 3 clinical trial dataChristina A Muzny, Olivia T Van Gerwen, Gregory Kaufman, Steven Chavoustie
7 August 2023
