Living systematic review and comprehensive network meta-analysis of ALS clinical trials: study protocolFloris T Van Loon, Georgios Seitidis, Dimitris Mavridis, Jordi W J van Unnik, Daphne N Weemering, Leonard H van den Berg, Ilianna Bethani, Stavros Nikolakopoulos, Ruben P A van Eijk
1 November 2024
Protocol for a phase 2 study of bosutinib for amyotrophic lateral sclerosis using real-world data: induced pluripotent stem cell-based drug repurposing for amyotrophic lateral sclerosis medicine (iDReAM) studyKeiko Imamura, Yuishin Izumi, Naohiro Egawa, Takashi Ayaki, Makiko Nagai, Kazutoshi Nishiyama, Yasuhiro Watanabe, Takenobu Murakami, Ritsuko Hanajima, Hiroshi Kataoka, Takao Kiriyama, Hitoki Nanaura, Kazuma Sugie, Takehisa Hirayama, Osamu KanoSee the full list of authors
26 October 2024
VAL-1221 for the treatment of patients with Lafora disease: study protocol for a single-arm, open-label clinical trialLorenzo Muccioli, Luca Vignatelli, Maria Tappatà, Serena Mazzone, Corrado Zenesini, Dustin Armstrong, DEFEAT-LD study group, Roberto Michelucci, Francesca Bisulli, DEFEAT-LD study group, Cosimo Altomare, Massimo Carella, Cinzia Costa, Giuseppe Damante, Lidia Di VitoSee the full list of authors
18 October 2024
Impact of dual sensory impairment on the risk of incident dementia: a protocol for a systematic review and meta-analysisStefano Giannoni-Luza, Daniele Urso, Ahmed Amine Alaoui, Jeremy Ting, Samir Jabbour, Adrian Fuente
17 October 2024
Post-rehabilitation programme to support upper limb recovery in community-dwelling stroke survivors: a mixed methods cluster-feasibility controlled trialKaty Pedlow, Niamh C Kennedy, Natalie Klempel, Janice J Eng, Gary Adamson, Jenny Hylands, Noelene Hughes, Zoe Campbell, Suzanne McDonough
15 October 2024
Epidemiology, tumour characteristics, treatment and outcomes associated with spinal nerve sheath tumours: a systematic review protocolOmar Ali Mahdi, Maria Gharios, Adnan Fatfat, Victor Gabriel El-Hajj, Aman Singh, Erik Edström, Adrian Elmi-Terander
11 October 2024
Deep brain stimulation versus vagus nerve stimulation for the motor function of poststroke hemiplegia: study protocol for a multicentre randomised controlled trialJunpeng Xu, Bin Liu, Guosong Shang, Shuzhen Liu, Zhebin Feng, Yanyang Zhang, Haonan Yang, Di Liu, Qing Chang, Chen Yuhan, Xinguang Yu, Zhiqi Mao
8 October 2024
Evaluating the effectiveness of simvastatin in slowing the progression of disability in secondary progressive multiple sclerosis (MS-STAT2): protocol for a multicentre, randomised controlled, double-blind, phase 3 clinical trial in the UKJames Blackstone, Thomas Williams, Jennifer M Nicholas, Ekaterina Bordea, Floriana De Angelis, Alessia Bianchi, Alberto Calvi, Anisha Doshi, Nevin John, Sean Apap Mangion, Charles Wade, Rachel Merry, Gil Barton, Dawn Lyle, Elisabeth JarmanSee the full list of authors
16 September 2024
Comparison of specialist ataxia centres with non-specialist services in terms of treatment, care, health services resource utilisation and costs in the UK using patient-reported dataJulie Vallortigara, Julie Greenfield, Barry Hunt, Deborah Hoffman, Suzanne Booth, Stephen Morris, Paola Giunti
5 September 2024
Association between apathy and caregiver burden in patients with amyotrophic lateral sclerosis: a cross-sectional studyZhenxiang Gong, Wenhua Deng, Zehui Li, Jiahui Tang, Min Zhang
3 September 2024