Rationale and design of a multicentre randomised controlled trial on circulating tumour DNA-guided neoadjuvant treatment strategy for locally advanced rectal cancer (CINTS-R)Jiaolin Zhou, Xiao Zhang, Qian Liu, Yongheng Li, Guoju Wu, Wei Fu, Hongwei Yao, Zhenjun Wang, Huadan Xue, Tao Xu, Weijie Chen, Junyang Lu, Guannan Zhang, Bin Wu, Yang AnSee the full list of authors
2 February 2025
Chinese herbal formula Tongxie Yaofang granules for diarrhoea-predominant irritable bowel syndrome: a randomised, double-blind, placebo-controlled, phase II trialShi-Bing Liang, Hong-Jie Cheng, Qiao-Yan Zhang, Mei Han, Yu-Fei Li, Hui-Juan Cao, Ze-Yu Yu, Ling-Yao Kong, Yan-Mei Cai, Li-Bao An, Bao-Tuan Zhao, Shan-Shan Xu, Ling Yan, Nai-Wei Zhang, Bo-Yi JiaSee the full list of authors
27 January 2025
Protocol for a first-in-human feasibility study of T regulatory cells (TR004) for inflammatory bowel disease using (ex vivo) Treg expansion (TRIBUTE)Beverley Rodger, Jennifer Clough, Joana Vasconcelos, James B Canavan, D Macallan, A Toby Prevost, Graham M Lord, Peter Irving
23 January 2025
Preoperative carcinoembryonic antigen to lymphocyte ratio serves as a prognostic predictor in elderly patients with colorectal cancer: a multicentre retrospective studyTao Liang, Jiayi Jiang, Xinyi Li, Haohan Ma, Xiaonan Zhang, Gang Deng, Weiping Deng, Lichang Guan, Kaijun Zhang, Lei Jiang, Ning Tan, Xujie Cai, Lishu Xu
20 January 2025
Randomised double-blind placebo-controlled trial protocol to evaluate the therapeutic efficacy of lyophilised faecal microbiota capsules amended with next-generation beneficial bacteria in individuals with metabolic dysfunction-associated steatohepatitisQuinten J. J. Augustijn, Aldo Grefhorst, Pleun de Groen, Koen Wortelboer, Jos F ML Seegers, Ismail Sahin Gül, Peter Suenaert, Joanne Verheij, Willem M. de Vos, Hilde Herrema, Max Nieuwdorp, Adriaan G. Holleboom
9 January 2025
Development and validation of a risk prediction model related to inflammatory and nutritional indexes for postoperative pulmonary infection after radical colorectal cancer surgeryJingxiang Han, Tian Yao, Linna Gao, Huiyang Gao, Yuhao Chen, Yanli Wang, Yinglei Cao, Chengfei Liu, Fubin Qiu, Kai Jia, He Huang
8 January 2025
Gastric cancer liver metastases in China: a real-world, multicentre, prospective, observational cohort study protocolTingting Lu, Yunhe Gao, Gan Zhang, Haiya Zhang, Zhida Chen, Yi Liu, Lin Chen, Hongqing Xi
8 January 2025
FAecal micRobiota transplantation in primary sclerosinG chOlangitis (FARGO): study protocol for a randomised, multicentre, phase IIa, placebo-controlled trialSarah Al-Shakhshir, Mohammed Nabil Quraishi, Benjamin Mullish, Arzoo Patel, Alexandra Vince, Anna Rowe, Victoria Homer, Nicola Jackson, Derick Gyimah, Sahida Shabir, Susan Manzoor, Rachel Cooney, Laith Alrubaiy, Christopher Quince, Willem van SchaikSee the full list of authors
6 January 2025
Antireflux mucosal valvuloplasty versus proton pump inhibitors for the treatment of patients with gastro-oesophageal reflux disease in a tertiary healthcare centre in China: study protocol for a randomised controlled trialXiaofen Lv, Wenlong Ma, Yunqing Zeng, Jiaoyang Lu
22 December 2024
Efficacy of susceptibility-guided quadruple therapy with antibiotic resistance using the string test coupled with quantitative PCR for Helicobacter pylori eradication: a protocol of a multicentre, open, randomised clinical trialYi Cui, Shenke Zhang, Shuqin Hu, Sujuan Fei, Geliang Yang
20 December 2024